What are PPIs?


Proton Pump Inhibitors (PPIs) are a group of heartburn drugs used for reducing of gastric acid production. Of all inhibitors of acid secretion available, PPIs are the strongest and most potent.



PPIs are some of the most widely sold drugs in the world. Many Americans buy PPIs to help with heartburn and acid reflux. Unfortunately, PPIs can lead to harmful side effects including kidney damage and complete renal failure.

What Symptoms Are Caused By PPIs?


  • Acute Kidney Injury

  • Acute Interstitial Nephritis

  • Chronic Kidney Disease

  • Kidney Failure

  • Dialysis Treatment

  • Kidney Transplant Surgery

  • Death

Why are PPIs Dangerous?


According to BioMed Journal, official case reports suggest that PPIs may be linked to acute kidney injury, which may lead to chronic renal injury or failure. This study was done to determine if there is a link between PPIs and kidney failure and renal disease.


The results were:


  1. Renal disease was positively associated with PPI use even after controlling for potential confounding conditions. After removing patients with potential confounding disease states from the study population, the number of cases and controls was lower, but the relationship between renal disease and PPI use remained consistent.

  2. Patients with a renal disease diagnosis were twice as likely to have used a prescription PPI.

  3. Studies show that regular use of Nexium has caused kidney disease and renal failure in some patients, which can cause serious injury or even death.

  4. Treating these kidney conditions can require dialysis, kidney transplant and grafts. The medical treatment of kidney failure is expensive and doesn’t always save a patient’s life.


The Journal of the American Society of Nephrology posted an official study in February of 2016, revealing the association between proton pump inhibitor (PPI) use and the risk of acute interstitial nephritis.


In February 2016, the Journal of the American Medical Association published a study indicating long-term use of PPI medications may increase the risk of developing chronic kidney disease (CKD). The study indicated that the 10-year risk of chronic kidney disease in PPI users was 20% -50% higher than those who had not taken the heartburn medications. The longer a person takes the medications, the greater the risk, and patients who took PPI medications more than once a day were more likely to develop kidney problems.


Our attorneys are reviewing kidney injury claims nationwide for PPI kidney failure cases.

If you have taken heartburn drugs like Prilosec, Prevacid or Nexium and suffered kidney damage, you may be entitled to financial compensation for your pain and suffering and medical expenses.


Although it has been used by millions of people and is widely thought to be safe, several studies suggest that side effects of Nexium and other PPIs may increase the risk of serious kidney problems, which were not adequately disclosed by the drug maker. If information had been provided to consumers and the medical community about the potential link between Nexium and kidney injury, many people may have avoided serious and life-threatening complications by limiting their use of the drug or choosing a different treatment alternative.

The US National Library of Medicine issued the following warning: “People who use certain drugs for chronic heartburn may be at increased risk of developing kidney disease, a new study suggests.”

What Can I Do?


Lawsuits have been filed against the manufacturers of Nexium and Prilosec for failing to warn patients and physicians of the increased risks of kidney disease and renal failure when using this medication.


If you have suffered from potentially dangerous side effects during or after taking Nexium or another PPI, you may be able to file a lawsuit against one of the PPI manufacturers.


You May Be Entitled to Significant Financial Compensation!


Plaintiffs who bring successful lawsuits against the manufacturers of Nexium and Prilosec may be eligible to receive compensation for their past and future medical bills, and pain and suffering. PPI lawsuits are mass torts, which means they are filed individually by each plaintiff and are not class actions.



If you or a loved one experienced any of these potentially serious side effects and are interested in more information regarding filing a heartburn drugs lawsuit, please fill out and submit the “Free Evaluation” form.




PRILOSEC® is a registered trademark of the AstraZeneca UK Limited and its Affiliates

NEXIUM® and the color purple as applied to the capsule are registered trademarks of the AstraZeneca UK Limited and its Affiliates

Did you or someone you know have kidney issues or stomach cancer after taking heartburn meds?


YOU may be entitled compensation for:

Past & Future Medical Bills

Pain & Suffering

Emotional Distress


We can help! Click below to see if you qualify - FREE! 

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The information on this website is for general information purposes only. Nothing on this site should be taken as legal advice for any individual case or situation. This information is not intended to create, and receipt or viewing does not constitute, an attorney-client relationship.